Young-onset dementia in individuals under 65 is often attributed to family history, but researchers emphasize that genetics is not the sole factor influencing the risk.
Depression, low socioeconomic status, social isolation: Inside the 15 risk factors for young-onset dementia (Photo: Google)
Unraveling 15 Risk Variables for Young-Onset Dementia
Various other factors beyond genetics play a role in increasing the susceptibility to young-onset dementia.
Young-onset dementia, which develops before 65, has 15 risk variables, according to JAMA Neurology observational research. Based on almost 350,000 U.K. patients, the study found characteristics associated with early dementia but could not prove causality. Depression, low socioeconomic position, vitamin D insufficiency, and hearing loss are these variables.
Exeter University researchers used the U.K. Biobank to assess 356,052 individuals with follow-ups in 2018 or 2021. During follow-up, 485 patients had young-onset dementia. Lower formal education, genetic markers, social isolation, and depression were risk factors for early dementia, showing its complexity.
READ ALSO: Sip Smart, Soak Sunshine: The Double Play Against Early-Onset Dementia!
Key Insights into Risk Factors for Young-Onset Dementia
Depression, poor socioeconomic position, and stroke were more strongly associated, while gender affected diabetes and C-reactive protein levels. The study showed that socioeconomic variables increase risk, especially for the poor. To better understand early dementia, handgrip strength, alcohol intake, and social interaction were identified as risk variables.
The study’s observational approach and overrepresentation of white individuals are drawbacks, but it helps uncover young-onset dementia risk factors. The findings highlight the need for larger investigations and inform dementia prevention efforts. The researchers noted the shift in dementia risk understanding and the opportunity for individual and societal treatments.
READ ALSO: Navigating The Impact Of Food-As-Medicine Program In Diabetes Care
